Rabbit Polyclonal Antibody to Kir5.1 (Ab-416)

包装: 1G|100G|500G|1KG|100KG

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别名:Inward rectifier K channel Kir5.1; IRK16; IRKG; KCNJ16; Potassium channel
应用:WB,IHC,ICC
反应种属:Human
规格：50μl/100μl

Description
Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.Liu Y., Cytogenet. Cell Genet. 90:60-63(2000).Derst C., FEBS Lett. 491:305-311(2001).

Description

Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. KCNJ16 may be involved in the regulation of fluid and pH balance.Liu Y., Cytogenet. Cell Genet. 90:60-63(2000).Derst C., FEBS Lett. 491:305-311(2001).

Specification
Aliases	Inward rectifier K channel Kir5.1; IRK16; IRKG; KCNJ16; Potassium channel
Entrez GeneID	3773;;
Swissprot	Q9NPI9
WB Predicted band size	48kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized non-phosphopeptide derived from human Kir5.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100
ICC	1/100-1/500

	Western blot analysis of extracts from HeLa cells, using Kir5.1 (Ab-416) antibody P41675.
	Immunofluorescence analysis of HeLa cells, using Kir5.1 (Ab-416) antibody P41675.
	Immunohistochemistry analysis of paraffin-embedded human brain tissue using Kir5.1 (Ab-416) antibody P41675.