Rabbit Polyclonal Antibody to KLF4(S254)

包装: 1G|100G|500G|1KG|100KG

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别名:Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Transcription factor; can act both as activator and as repressor. Binds the 5′-CACCC-3′ core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Description

Transcription factor; can act both as activator and as repressor. Binds the 5′-CACCC-3′ core sequence. Binds to the promoter region of its own gene and can activate its own transcription. Regulates the expression of key transcription factors during embryonic development. Plays an important role in maintaining embryonic stem cells, and in preventing their differentiation. Required for establishing the barrier function of the skin and for postnatal maturation and maintenance of the ocular surface. Involved in the differentiation of epithelial cells and may also function in skeletal and kidney development. Contributes to the down-regulation of p53/TP53 transcription.

Specification
Aliases	Krueppel-like factor 4, Epithelial zinc finger protein EZF, Gut-enriched krueppel-like factor, KLF4, EZF, GKLF
Entrez GeneID	9314
Swissprot	O43474
WB Predicted band size	54.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This KLF4(S254) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human KLF4(S254).