中文 
别名:Kelch-like protein 3; KIAA1129;应用:WB,IHC,ICC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.Lai F., Genomics 66:65-75(2000).Hirosawa M., DNA Res. 6:329-336(1999).Ota T., Nat. Genet. 36:40-45(2004). |
| Specification | |
|---|---|
| Aliases | Kelch-like protein 3; KIAA1129; |
| Entrez GeneID | 26249; |
| Swissprot | Q9UH77 |
| WB Predicted band size | 65kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from N-terminal of human KLHL3. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
| IHC | 1/50-1/100 |
| ICC | 1/100-1/500 |
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Western blot analysis of extracts from RAW264.7 cells and 3T3 cells, using KLHL3 antibody P42129. |
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Immunofluorescence analysis of A549 cells, using KLHL3 antibody P42129. |
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Immunohistochemistry analysis of paraffin-embedded human brain tissue, using KLHL3 antibody P42129. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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