Rabbit Polyclonal Antibody to KLK10 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Kallikrein-10, 3421-, Normal epithelial cell-specific 1, Protease serine-like 1, KLK10, NES1, PRSSL1
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq].

Description

Kallikreins are a subgroup of serine proteases having
diverse physiological functions. Growing evidence suggests that
many kallikreins are implicated in carcinogenesis and some have
potential as novel cancer and other disease biomarkers. This gene
is one of the fifteen kallikrein subfamily members located in a
cluster on chromosome 19. Its encoded protein is secreted and may
play a role in suppression of tumorigenesis in breast and prostate
cancers. Alternate splicing of this gene results in multiple
transcript variants encoding the same protein. [provided by
RefSeq].

Specification
Aliases	Kallikrein-10, 3421-, Normal epithelial cell-specific 1, Protease serine-like 1, KLK10, NES1, PRSSL1
Entrez GeneID	5655
Swissprot	O43240
WB Predicted band size	30.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This KLK10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 22-51 amino acids from the N-terminal region of human KLK10.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000

	KLK10 Antibody (N-term) (Cat. #P31493) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the KLK10 antibody detected the KLK10 protein (arrow).
	Western blot analysis of KLK10 (arrow) using rabbit polyclonal KLK10 Antibody (N-term) (Cat. #P31493). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the KLK10 gene.