Rabbit Polyclonal Antibody to KLK2

包装: 1G|100G|500G|1KG|100KG

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别名:hK2; hGK-1; KLK2A2
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Description

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants.

Specification
Aliases	hK2; hGK-1; KLK2A2
Entrez GeneID	3817;
Swissprot	P20151
WB Predicted band size	29kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide corresponding to residues near the C terminal of human kallikrein-related peptidase 2
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
WB	1/500-1/2000
IHC	1/100-1/300

	Gel: 10%SDS-PAGE Lysate: 40ug Hela cell Primary antibody: 1/1650 dilution Secondary antibody dilution: 1/8000 Exposure time: 2 minutes
	Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using P42860 at dilution 1/80.