Rabbit Polyclonal Antibody to L3MBTL2

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别名:L3MBT; H-l(3)mbt-l
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ‘Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ‘Lys-4’, ‘Lys-9’ or ‘Lys-27’.

Description

Putative Polycomb group (PcG) protein. PcG proteins maintain the transcriptionally repressive state of genes, probably via a modification of chromatin, rendering it heritably changed in its expressibility. Its association with a chromatin-remodeling complex suggests that it may contribute to prevent expression of genes that trigger the cell into mitosis. Binds to monomethylated and dimethylated ‘Lys-20’ on histone H4. Binds histone H3 peptides that are monomethylated or dimethylated on ‘Lys-4’, ‘Lys-9’ or ‘Lys-27’.

Specification
Aliases	L3MBT; H-l(3)mbt-l
Swissprot	Q969R5
WB Predicted band size	79 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human L3MBTL2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/100
ELISA	1/5000-1/10000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse thymus tissue lysate, Primary antibody: P03219(L3MBTL2 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 35 seconds
	The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P03219(L3MBTL2 Antibody) at dilution 1/60. (Original magnification: ×200)