Rabbit Polyclonal Antibody to LGALS3

包装: 1G|100G|500G|1KG|100KG

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别名:Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2
应用:WB,FCM
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. Alternate splicing results in multiple transcript variants.

Description

This gene encodes a member of the galectin family of
carbohydrate binding proteins. Members of this protein family have
an affinity for beta-galactosides. The encoded protein is
characterized by an N-terminal proline-rich tandem repeat domain
and a single C-terminal carbohydrate recognition domain. This
protein can self-associate through the N-terminal domain allowing
it to bind to multivalent saccharide ligands. This protein
localizes to the extracellular matrix, the cytoplasm and the
nucleus. This protein plays a role in numerous cellular functions
including apoptosis, innate immunity, cell adhesion and T-cell
regulation. Alternate splicing results in multiple transcript
variants.

Specification
Aliases	Galectin-3, Gal-3, 35 kDa lectin, Carbohydrate-binding protein 35, CBP 35, Galactose-specific lectin 3, Galactoside-binding protein, GALBP, IgE-binding protein, L-31, Laminin-binding protein, Lectin L-29, Mac-2 antigen, LGALS3, MAC2
Entrez GeneID	3958
Swissprot	P17931
WB Predicted band size	26.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This LGALS3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 163-191 amino acids from the C-terminal region of human LGALS3.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	LGALS3 Antibody (C-term) (Cat. #P31016) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the LGALS3 antibody detected the LGALS3 protein (arrow).
	LGALS3 Antibody (C-term) (Cat. #P31016) flow cytometric analysis of MCF-7 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.