Rabbit Polyclonal Antibody to LINGO1

包装: 1G|100G|500G|1KG|100KG

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别名:LERN1; MRT64; LRRN6A; UNQ201
应用:IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Description

Functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors (PubMed:14966521, PubMed:15694321). Is also an important negative regulator of oligodentrocyte differentiation and axonal myelination (PubMed:15895088). Acts in conjunction with RTN4 and RTN4R in regulating neuronal precursor cell motility during cortical development (By similarity).

Specification
Aliases	LERN1; MRT64; LRRN6A; UNQ201
Swissprot	Q96FE5
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human LINGO1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12771(LINGO1 Antibody) at dilution 1/50. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P12771(LINGO1 Antibody) at dilution 1/50. (Original magnification: ×200)