Rabbit Polyclonal Antibody to LTA

包装: 1G|100G|500G|1KG|100KG

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别名:LT; TNFB; TNFSF1
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin’s lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

Description

The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin’s lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene.

Specification
Aliases	LT; TNFB; TNFSF1
Entrez GeneID	4049;
Swissprot	P01374
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein corresponding to a region derived from internal residues of human lymphotoxin alpha (TNF superfamily, member 1)
Formulation	Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

Application
IHC	1/50-1/200

	Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42789 at dilution 1/50.
	Immunohistochemical analysis of paraffin-embedded Human lung cancer tissue using P42789 at dilution 1/50.