中文 
别名:CSF1R; C-FMS; CD115; CSFR;应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development. Sampaio NG, et al. (2011) J Cell Sci 124, 2021-31 21610095 Curated InfoXiong Y, et al. (2011) J Biol Chem 286, 952-60 21041311 Curated InfoYu W, et al. (2008) J Leukoc Biol 84, 852-63 |
| Specification | |
|---|---|
| Aliases | CSF1R; C-FMS; CD115; CSFR; |
| Entrez GeneID | 1436; |
| Swissprot | P07333 |
| WB Predicted band size | 108kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of tyrosine 809 (S-N-Y(p)-I-V) derived from Human M-CSF Receptor. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from 293 cells treated with LPS using Phospho-M-CSF Receptor (Tyr809) antibody P40547.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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