Rabbit Polyclonal Antibody to MAEA

包装: 1G|100G|500G|1KG|100KG

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别名:Macrophage erythroblast attacher; Erythroblast macrophage protein; Cell proliferation-inducing gene 5 protein; Lung cancer-related protein 10; HLC-10
应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.Ota T., Nat. Genet. 36:40-45(2004).Hanspal M., Blood 92:2940-2950(1998).Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006).

Description

Plays a role in erythroblast enucleation and in the development of the mature macrophages. Mediates the attachment of erythroid cell to mature macrophages, in correlation with the presence of MAEA at cell surface of mature macrophages; This MAEA-mediated contact inhibits erythroid cells apoptosis. Participates to erythroblastic island formation, which is the functional unit of definitive erythropoiesis. Associates with F-actin to regulate actin distribution in erythroblasts and macrophages. May contribute to nuclear architecture and cells division events.Ota T., Nat. Genet. 36:40-45(2004).Hanspal M., Blood 92:2940-2950(1998).Bala S., Biochem. Biophys. Res. Commun. 342:1040-1048(2006).

Specification
Aliases	Macrophage erythroblast attacher; Erythroblast macrophage protein; Cell proliferation-inducing gene 5 protein; Lung cancer-related protein 10; HLC-10
Entrez GeneID	10296;
Swissprot	Q7L5Y9
WB Predicted band size	45kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from internal of human MAEA.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.