库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to MANF

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别名:ARP; ARMET
应用:IHC
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
The protein encoded by this gene is localized in the endoplasmic reticulum (ER) and golgi, and is also secreted. Reducing expression of this gene increases susceptibility to ER stress-induced death and promotes cell proliferation. The protein was initially thought to be longer at the N-terminus and to contain an arginine-rich region but transcribed evidence indicates a smaller open reading frame that does not encode the arginine tract. The presence of polymorphisms in the arginine-rich region, including a specific mutation that changes the previously numbered codon 50 from ATG to AGG, have been reported in a variety of solid tumors; however, these polymorphisms were later shown to exist in normal tissues and are thus not tumor-related.
Specification
Aliases ARP; ARMET
Entrez GeneID 7873;
Swissprot P55145
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen Synthetic peptide corresponding to residues near the C terminal of human mesencephalic astrocyte-derived neurotrophic factor
Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Application
IHC 1/100-1/300

Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42913 at dilution 1/70.
Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42913 at dilution 1/70.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。