Rabbit Polyclonal Antibody to MAPK1/MAPK3

包装: 1G|100G|500G|1KG|100KG

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别名:ERK1, ERK2, ERK1/2
应用:WB,IHC
反应种属:Human, Mouse,Rat
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Description

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.

Specification
Aliases	ERK1, ERK2, ERK1/2
Swissprot	P28482/P27361
WB Predicted band size	41 kDa; 43 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse,Rat
Immunogen	Synthetic peptide of human MAPK1/MAPK3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1/2000-1/5000

	Gel: 8%SDS-PAGE,Lysate: 40 μg,Lane 1-4: 293T cells, Human brain malignant glioma tissue, Mouse brain tissue, Human hepatocellsular carcinoma tissue,Primary antibody: P03906(MAPK1/MAPK3 Antibody) at dilution 1/550 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 20 seconds
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P03906(MAPK1/MAPK3 Antibody) at dilution 1/30. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human brain tissue using P03906(MAPK1/MAPK3 Antibody) at dilution 1/30. (Original magnification: ×200)