Rabbit Polyclonal Antibody to MAPK8IP3

包装: 1G|100G|500G|1KG|100KG

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别名:syd; JIP3; SYD2; JIP-3; JSAP1
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Description

The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specification
Aliases	syd; JIP3; SYD2; JIP-3; JSAP1
Swissprot	Q9UPT6
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthetic peptide of human MAPK8IP3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/40-1/200
ELISA	1/5000-1/10000

	The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P06776(MAPK8IP3 Antibody) at dilution 1/45. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P06776(MAPK8IP3 Antibody) at dilution 1/45. (Original magnification: ×200)