Rabbit Polyclonal Antibody to MBL2

包装: 1G|100G|500G|1KG|100KG

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别名:Mannose-binding protein C, MBP-C, Collectin-1, MBP1, Mannan-binding protein, Mannose-binding lectin, MBL2, COLEC1, MBL
应用:WB,IHC,ICC
反应种属:Human
规格：50μl/100μl

Description
This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes mannose and N-acetylglucosamine on many microorganisms, and is capable of activating the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

Description

This gene encodes the soluble mannose-binding lectin or
mannose-binding protein found in serum. The protein encoded belongs
to the collectin family and is an important element in the innate
immune system. The protein recognizes mannose and
N-acetylglucosamine on many microorganisms, and is capable of
activating the classical complement pathway. Deficiencies of this
gene have been associated with susceptibility to autoimmune and
infectious diseases.

Specification
Aliases	Mannose-binding protein C, MBP-C, Collectin-1, MBP1, Mannan-binding protein, Mannose-binding lectin, MBL2, COLEC1, MBL
Entrez GeneID	4153
Swissprot	P11226
WB Predicted band size	26.1kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This MBL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-202 amino acids from the C-terminal region of human MBL2.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
ICC	1/10-1/50

	MBL2 Antibody (C-term) (Cat. #P31331) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the MBL2 antibody detected the MBL2 protein (arrow).
	Western blot analysis of MBL2 (arrow) using rabbit polyclonal MBL2 Antibody (C-term) (Cat. #P31331). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MBL2 gene.
	Confocal immunofluorescent analysis of MBL2 Antibody (C-term)(Cat#P31331) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
	MBL2 Antibody (C-term) (Cat. #P31331)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MBL2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.