Rabbit Polyclonal Antibody to MED13

包装: 1G|100G|500G|1KG|100KG

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别名:ARC250; Activator-recruited cofactor 250 kDa component; KIAA0593; T240; THRAP1
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Olsen J.V., Cell 127:635-648(2006).Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).Naeaer A.M., Nature 398:828-832(1999).

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Olsen J.V., Cell 127:635-648(2006).Beausoleil S.A., Proc. Natl. Acad. Sci. U.S.A. 101:12130-12135(2004).Naeaer A.M., Nature 398:828-832(1999).

Specification
Aliases	ARC250; Activator-recruited cofactor 250 kDa component; KIAA0593; T240; THRAP1
Entrez GeneID	9969;
Swissprot	Q9UHV7
WB Predicted band size	240kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human MED13.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.