Rabbit Polyclonal Antibody to MED24

包装: 1G|100G|500G|1KG|100KG

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别名:100 kDa thyroid hormone receptor associated protein; ARC100; Activator-recruited cofactor 100 kDa component; DRIP100; KIAA0130
应用:WB,ICC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).Rachez C., Genes Dev. 12:1787-1800(1998).Nagase T., DNA Res. 2:167-174(1995).

Description

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).Rachez C., Genes Dev. 12:1787-1800(1998).Nagase T., DNA Res. 2:167-174(1995).

Specification
Aliases	100 kDa thyroid hormone receptor associated protein; ARC100; Activator-recruited cofactor 100 kDa component; DRIP100; KIAA0130
Entrez GeneID	9862;
Swissprot	O75448
WB Predicted band size	110kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from internal of human MED24.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
ICC	1/100-1/500

	Western blot analysis of extracts from 293 cells, using MED24 antibody P41882.
	Immunofluorescence analysis of HUVEC cells, using MED24 antibody P41882.