中文 
别名:EC 2.7.11.1; HPK/GCK-like kinase HGK; M4K4; MAP4K4; MAPK/ERK kinase kinase kinase 4应用:WB,ICC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Serine/threonine kinase that may play a role in the response to environmental stress and cytokines such as TNF-alpha. Appears to act upstream of the JUN N-terminal pathway. Phosphorylates SMAD1 on Thr-322.Yao Z., J. Biol. Chem. 274:2118-2125(1999).Wright J.H., Mol. Cell. Biol. 23:2068-2082(2003).Ishikawa K., DNA Res. 5:169-176(1998). |
| Specification | |
|---|---|
| Aliases | EC 2.7.11.1; HPK/GCK-like kinase HGK; M4K4; MAP4K4; MAPK/ERK kinase kinase kinase 4 |
| Entrez GeneID | 9448; |
| Swissprot | O95819 |
| WB Predicted band size | 142kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human MEKKK 4. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
| ICC | 1/100-1/500 |
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Western blot analysis of extracts from COLO cells and HUVEC cells, using MEKKK 4 antibody P41895. |
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Immunofluorescence analysis of A549 cells, using MEKKK 4 antibody P41895. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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