Rabbit Polyclonal Antibody to MKL1

包装: 1G|100G|500G|1KG|100KG

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别名:Myocardin-related transcription factor A; MRTF-A; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein;
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.Ma Z., Nat. Genet. 28:220-221(2001).Mercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).Nagase T., DNA Res. 7:65-73(2000).

Description

Transcriptional coactivator of serum response factor (SRF) with the potential to modulate SRF target genes. Suppresses TNF-induced cell death by inhibiting activation of caspases; its transcriptional activity is indispensable for the antiapoptotic function. It may up-regulate antiapoptotic molecules, which in turn inhibit caspase activation By similarity.Ma Z., Nat. Genet. 28:220-221(2001).Mercher T., Proc. Natl. Acad. Sci. U.S.A. 98:5776-5779(2001).Nagase T., DNA Res. 7:65-73(2000).

Specification
Aliases	Myocardin-related transcription factor A; MRTF-A; Megakaryoblastic leukemia 1 protein; Megakaryocytic acute leukemia protein;
Entrez GeneID	57591;
Swissprot	Q969V6
WB Predicted band size	99kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from N-terminal of human MKL1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.