中文 
别名:M3K9; PRKE1; mixed-lineage protein kinase 1;应用:IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.Durkin J.T., Biochemistry 43:16348-16355(2004)The MGC Project Team; Genome Res. 14:2121-2127(2004)Dorow D.S.,Nature 446:153-158(2007). |
| Specification | |
|---|---|
| Aliases | M3K9; PRKE1; mixed-lineage protein kinase 1; |
| Entrez GeneID | 4293; |
| Swissprot | P80192 |
| WB Predicted band size | 121kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Peptide sequence around phosphorylation site of threonine 312/266(A-G-T(p)-Y-A) derived from Human MLK1/2. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IHC | 1/50-1/100 |
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Immunohistochemical analysis of paraffin-embedded human brain tissue using MLK1/2 (Phospho-Thr312/266) antibody P40447 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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