中文 
别名:EC 2.7.11.1; kinase Mnk1; Map kinase interacting kinase; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.Fukunaga R., EMBO J. 16:1921-1933(1997).Knauf U., Mol. Cell. Biol. 21:5500-5511(2001).O’Loghlen A., Exp. Cell Res. 299:343-355(2004). |
| Specification | |
|---|---|
| Aliases | EC 2.7.11.1; kinase Mnk1; Map kinase interacting kinase; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1 |
| Entrez GeneID | 8569; |
| Swissprot | Q9BUB5 |
| WB Predicted band size | 45kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized non-phosphopeptide derived from human Mnk1 around the phosphorylation site of threonine 385 (L-P-T(p)-P-Q). |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
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Western blot analysis of extracts from 3T3 cells, treated with PMA (125ng/ml, 30mins), using Mnk1 (Ab-385) antibody P41758. |
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Western blot analysis of extracts from HepG2 cells (Lane 2), K562 cells (Lane 3) and Jurket cells (Lane 4), using Mnk1 (Ab-385) antiobdy P41758. The lane on the left is treated with systhesized peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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