中文 
别名:Chromobox protein homolog 7, Cbx7, D15Ertd417e应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl
| Description |
|---|
| Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A ‘Lys-119’, rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at ‘Lys-9’ (H3K9me3). Binds to histone H3 trimethylated ‘Lys-9’ (H3K9me3) or at ‘Lys-27’ (H3K27me3). May possibly also bind trimethylated lysine residues in other proteins (in vitro). Binds non-coding, single-stranded RNA. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity. |
| Specification | |
|---|---|
| Aliases | Chromobox protein homolog 7, Cbx7, D15Ertd417e |
| Entrez GeneID | 52609 |
| Swissprot | Q8VDS3 |
| WB Predicted band size | 18.1kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This Mouse Cbx7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-178 amino acids from the C-terminal region of human Mouse Cbx7. |
| Application | |
|---|---|
| WB | 1/1000 |
 |
Western blot analysis of lysates from Hela cell line, mouse brain, mouse testis, mouse lung, mouse spleen, rat brain tissue (from left to right), using Mouse Cbx7 Antibody (C-term)(Cat. #P32884). P32884 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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