别名:Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
| Description |
|---|
| Transcriptional repressor of genes that require a bHLH protein for their transcription. May act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1 (By similarity). Binds DNA on N-box motifs: 5′-CACNAG-3′ with high affinity and on E-box motifs: 5′-CANNTG-3′ with low affinity. May play a role in a functional FA core complex response to DNA cross- link damage, being required for the stability and nuclear localization of FA core complex proteins, as well as for FANCD2 monoubiquitination in response to DNA damage (By similarity). |
| Specification | |
|---|---|
| Aliases | Transcription factor HES-1, Hairy and enhancer of split 1, Hes1, Hes-1 |
| Entrez GeneID | 15205 |
| Swissprot | P35428 |
| WB Predicted band size | 29.7kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This Mouse Hes1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 205-239 amino acids from the C-terminal region of Mouse Hes1. |
| Application | |
|---|---|
| WB | 1/500 |
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Western blot analysis of lysate from mouse kidney tissue lysate, using Hes1 Antibody (C-term)(Cat. #P32911). P32911 was diluted at 1:500. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysate at 20ug. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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