别名:Transcription factor SOX-17, Sox17, Sox-17应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
| Description |
|---|
| Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5′- AACAAT-‘3 or 5′-AACAAAG-3’. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells. Isoform 2 (T-SOX17) shows no DNA-binding activity. |
| Specification | |
|---|---|
| Aliases | Transcription factor SOX-17, Sox17, Sox-17 |
| Entrez GeneID | 20671 |
| Swissprot | Q61473 |
| WB Predicted band size | 44.6kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This (Mouse) Sox17 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 376-409 amino acids from the C-terminal region of human (Mouse) Sox17. |
| Application | |
|---|---|
| WB | 1/1000 |
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Western blot analysis of lysates from LNCaP, mouse F9 cell line (from left to right), using Sox17 Antibody (C-term)(Cat. #P32807). P32807 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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