别名:Transcription factor SOX-2, Sox2, Sox-2应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl
| Description |
|---|
| Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity). |
| Specification | |
|---|---|
| Aliases | Transcription factor SOX-2, Sox2, Sox-2 |
| Entrez GeneID | 20674 |
| Swissprot | P48432 |
| WB Predicted band size | 34.5kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | This Mouse Sox2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 6~39 amino acids from the N-terminal region of mouse sox2. |
| Application | |
|---|---|
| WB | 1/1000 |
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Western blot analysis of lysates from NCCIT, mouse F9 cell line (from left to right), using Sox2 Antibody (N-term)(Cat. #P32845). P32845 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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