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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to Mouse TSC1 (C-term S1138)

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别名:Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
应用:WB
反应种属:Mouse
规格:50μl/100μl

Description
In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling (By similarity). Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling (By similarity).
Specification
Aliases Hamartin, Tuberous sclerosis 1 protein homolog, Tsc1, Kiaa0243
Entrez GeneID 64930
Swissprot Q9EP53
WB Predicted band size 128.7kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Mouse
Immunogen This Mouse TSC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1117-1144 amino acids from the C-terminal region of mouse TSC1.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

Anti-Mouse TSC1 Antibody (S1138) at 1:1000 dilution + mouse liver lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 129 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.


本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。