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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to (Mouse) Wdr5

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别名:WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WD repeat-containing protein BIG-3, Wdr5, Big, Big3
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
Contributes to histone modification. May position the N- terminus of histone H3 for efficient trimethylation at ‘Lys-4’. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ‘Lys-4’ of histone H3. H3 ‘Lys-4’ methylation represents a specific tag for epigenetic transcriptional activation. As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues. May regulate osteoblasts differentiation (By similarity).
Specification
Aliases WD repeat-containing protein 5, BMP2-induced 3-kb gene protein, WD repeat-containing protein BIG-3, Wdr5, Big, Big3
Entrez GeneID 140858
Swissprot P61965
WB Predicted band size 36.6kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen This Mouse Wdr5 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the region of mouse Wdr5.
Application
WB 1/1000

Western blot analysis of lysates from human liver tissue and mouse NIH/3T3 cell line(from left to right), using (Mouse) Wdr5 Antibody(Cat. #P32849). P32849 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:10000 dilution was used as the secondary antibody. Lysates at 20ug per lane.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。