Rabbit Polyclonal Antibody to MOV10 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Putative helicase MOV-10, Moloney leukemia virus 10 protein, MOV10, KIAA1631
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.

Description

Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hapatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.

Specification
Aliases	Putative helicase MOV-10, Moloney leukemia virus 10 protein, MOV10, KIAA1631
Entrez GeneID	4343
Swissprot	Q9HCE1
WB Predicted band size	113.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This MOV10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 260-288 amino acids from the N-terminal region of human MOV10.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	MOV10 Antibody (N-term) (Cat. #P31560) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the MOV10 antibody detected the MOV10 protein (arrow).
	MOV10 Antibody (N-term) (P31560)immunohistochemistry analysis in formalin fixed and paraffin embedded human heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MOV10 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.