Rabbit Polyclonal Antibody to MPP3

包装: 1G|100G|500G|1KG|100KG

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别名:MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3, MPP3, DLG3
应用:WB,ICC,FCM
反应种属:Human
规格：50μl/100μl

Description
This gene product is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. This protein contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. Alternatively spliced transcript variants have been identified. One transcript variant is experimentally supported, but it doesn’t encode a protein.

Description

This gene product is a member of a family of
membrane-associated proteins termed MAGUKs (membrane-associated
guanylate kinase homologs). MAGUKs interact with the cytoskeleton
and regulate cell proliferation, signaling pathways, and
intracellular junctions. This protein contains a conserved
sequence, called the SH3 (src homology 3) motif, found in several
other proteins that associate with the cytoskeleton and are
suspected to play important roles in signal transduction.
Alternatively spliced transcript variants have been identified. One
transcript variant is experimentally supported, but it doesn’t
encode a protein.

Specification
Aliases	MAGUK p55 subfamily member 3, Discs large homolog 3, Protein MPP3, MPP3, DLG3
Entrez GeneID	4356
Swissprot	Q13368
WB Predicted band size	66.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This MPP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 406-434 amino acids from the C-terminal region of human MPP3.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
ICC	1/10-1/50
FCM	1/10-1/50

	Anti-MPP3 Antibody (C-term) at 1:1000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 66 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
	MPP3 Antibody (C-term) (Cat. #P33730) western blot analysis in K562,NCI-H292 cell line lysates (35ug/lane).This demonstrates the MPP3 antibody detected the MPP3 protein (arrow).
	Confocal immunofluorescent analysis of MPP3 Antibody (C-term)(Cat#P33730) with MDA-MB231 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
	MPP3 Antibody (C-term) (Cat. #P33730) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.