中文 
别名:Myosin phosphatase Rho-interacting protein; Rho-interacting protein 3; M-RIP; RIP3; p116Rip应用:IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells. UniProtKB P97434Surks H.K., J. Biol. Chem. 278:51484-51493(2003).Koga Y., J. Biol. Chem. 280:4983-4991(2005).Inazawa J., Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases. |
| Specification | |
|---|---|
| Aliases | Myosin phosphatase Rho-interacting protein; Rho-interacting protein 3; M-RIP; RIP3; p116Rip |
| Entrez GeneID | 23164; |
| Swissprot | Q6WCQ1 |
| WB Predicted band size | 117kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human MPRIP. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IHC | 1/50-1/100 |
 |
Immunohistochemistry analysis of paraffin-embedded human lymph node tissue using MPRIP antibody P42479. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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