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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to MPZ

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别名:P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB
应用:IHC
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
This gene encodes a major structural protein of peripheral myelin. Mutations in this gene result in the autosomal dominant form of Charcot-Marie-Tooth disease type 1 and other polyneuropathies. The myelin sheath is a multi-layered membrane, unique to the nervous system, that functions as an insulator to greatly increase the velocity of axonal impulse conduction. The P0 glycoprotein, absent in the central nervous system,[1] is a major component of the myelin sheath in peripheral nerves. It comprises a large extracellular N-terminal domain, a single transmembrane (TM) region, and a smaller positively charged intracellular domain.
Specification
Aliases P0; CHM; DSS; MPP; CMT1; CMT1B; CMT2I; CMT2J; CMT4E; CMTDI3; CMTDID; HMSNIB
Swissprot P25189
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human MPZ
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
IHC 1/15-1/50
ELISA 1/1000-1/2000

The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07466(MPZ Antibody) at dilution 1/5. (Original magnification: ×200)

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。