Rabbit Polyclonal Antibody to MRPL1

包装: 1G|100G|500G|1KG|100KG

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别名:l10mt; mgc17973; mitochondrial ribosomal protein l10; mrp-l10; mrp-l8
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q.The MGC Project Team; Genome Res. 14:2121-2127(2004).Kenmochi N., Genomics 77:65-70(2001).Koc E.C., J. Biol. Chem. 276:43958-43969(2001)

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q.The MGC Project Team; Genome Res. 14:2121-2127(2004).Kenmochi N., Genomics 77:65-70(2001).Koc E.C., J. Biol. Chem. 276:43958-43969(2001)

Specification
Aliases	l10mt; mgc17973; mitochondrial ribosomal protein l10; mrp-l10; mrp-l8
Entrez GeneID	124995;
Swissprot	Q7Z7H8
WB Predicted band size	29kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human MRPL10.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.