Rabbit Polyclonal Antibody to MRPL15

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别名:39S ribosomal protein L15; mitochondrial [Precursor]; L15mt; MRP-L15; HSPC145
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.Zhang Q.-H., Genome Res. 10:1546-1560(2000).Wiemann S., Genome Res. 11:422-435(2001).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q.Zhang Q.-H., Genome Res. 10:1546-1560(2000).Wiemann S., Genome Res. 11:422-435(2001).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Specification
Aliases	39S ribosomal protein L15; mitochondrial [Precursor]; L15mt; MRP-L15; HSPC145
Entrez GeneID	29088;
Swissprot	Q9P015
WB Predicted band size	33kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human MRPL15.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.