别名:39S ribosomal protein L49; mitochondrial; C11orf4; L49mt; MGC10656应用:WB
反应种属:Human
规格:50μl/100μl
Description |
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p.Kas K., Genomics 34:433-436(1996).Shichijo S., Submitted (MAY-2001) to the EMBL/GenBank/DDBJ databases.Ota T., Nat. Genet. 36:40-45(2004). |
Specification | |
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Aliases | 39S ribosomal protein L49; mitochondrial; C11orf4; L49mt; MGC10656 |
Entrez GeneID | 740; |
Swissprot | Q13405 |
WB Predicted band size | 20kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from Internal of human MRPL49. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from HeLa/COLO205 cells, using MRPL49 antibody P42471. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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