Rabbit Polyclonal Antibody to MRPS36

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别名:DC47; mitochondrial 28S ribosomal protein S36; MRP-S36; RT36; S36mt
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p.Xu X., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.The MGC Project Team; Genome Res. 14:2121-2127(2004).Koc E.C., J. Biol. Chem. 276:19363-19374(2001).

Description

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. The mitochondrial ribosome (mitoribosome) consists of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. Pseudogenes corresponding to this gene are found on chromosomes 3p, 4q, 8p, 11q, 12q, and 20p.Xu X., Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.The MGC Project Team; Genome Res. 14:2121-2127(2004).Koc E.C., J. Biol. Chem. 276:19363-19374(2001).

Specification
Aliases	DC47; mitochondrial 28S ribosomal protein S36; MRP-S36; RT36; S36mt
Entrez GeneID	92259;
Swissprot	P82909
WB Predicted band size	15kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human MRPS36.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from HepG2 cells, using MRPS36 antibody P42468.
	Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using MRPS36 antibody P42468.