别名:CRS2; FPP; Homeobox protein Hox-8; Homeobox protein MSX-2; HOX8应用:WB
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.Hodgkinson J.E., Biochim. Biophys. Acta 1174:11-16(1993).Jabs E.W., Cell 75:443-450(1993).Iimura T., DNA Seq. 8:87-92(1997). |
Specification | |
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Aliases | CRS2; FPP; Homeobox protein Hox-8; Homeobox protein MSX-2; HOX8 |
Entrez GeneID | 4488; |
Swissprot | P35548 |
WB Predicted band size | 29kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Synthesized peptide derived from Internal of human MSX2. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
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Western blot analysis of extracts from COLO205 cells, using MSX2 antibody P42437. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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