Rabbit Polyclonal Antibody to MSX2

包装: 1G|100G|500G|1KG|100KG

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别名:CRS2; FPP; Homeobox protein Hox-8; Homeobox protein MSX-2; HOX8
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.Hodgkinson J.E., Biochim. Biophys. Acta 1174:11-16(1993).Jabs E.W., Cell 75:443-450(1993).Iimura T., DNA Seq. 8:87-92(1997).

Description

Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter.Hodgkinson J.E., Biochim. Biophys. Acta 1174:11-16(1993).Jabs E.W., Cell 75:443-450(1993).Iimura T., DNA Seq. 8:87-92(1997).

Specification
Aliases	CRS2; FPP; Homeobox protein Hox-8; Homeobox protein MSX-2; HOX8
Entrez GeneID	4488;
Swissprot	P35548
WB Predicted band size	29kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from Internal of human MSX2.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.