Rabbit Polyclonal Antibody to MYO5B (N-Term)

包装: 1G|100G|500G|1KG|100KG

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别名:Unconventional myosin-Vb, MYO5B, KIAA1119
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.

Description

May be involved in vesicular trafficking via its association with the CART complex. The CART complex is necessary for efficient transferrin receptor recycling but not for EGFR degradation. Required in a complex with RAB11A and RAB11FIP2 for the transport of NPC1L1 to the plasma membrane. Together with RAB11A participates in CFTR trafficking to the plasma membrane and TF (transferrin) recycling in nonpolarized cells. Together with RAB11A and RAB8A participates in epithelial cell polarization. Together with RAB25 regulates transcytosis.

Specification
Aliases	Unconventional myosin-Vb, MYO5B, KIAA1119
Entrez GeneID	4645
Swissprot	Q9ULV0
WB Predicted band size	213.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This MYO5B antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 7-30 amino acids from MYO5B.