Rabbit Polyclonal Antibody to Myosin 1C (MYO1C)

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Unconventional myosin-Ic, Myosin I beta, MMI-beta, MMIb, MYO1C
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.

Description

MYO1C is a member of the unconventional myosin protein family, which are actin-based molecular motors. The protein is found in the cytoplasm, and one isoform with a unique N-terminus is also found in the nucleus. The nuclear isoform associates with RNA polymerase I and II and functions in transcription initiation. The mouse ortholog of this protein also functions in intracellular vesicle transport to the plasma membrane.

Specification
Aliases	Unconventional myosin-Ic, Myosin I beta, MMI-beta, MMIb, MYO1C
Entrez GeneID	4641
Swissprot	O00159
WB Predicted band size	121.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This Myosin 1C (MYO1C) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 911-940 amino acids from the C-terminal region of human Myosin 1C (MYO1C).
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Application
WB	1/1000
IHC	1/100-1/500

	Western blot analysis of MYO1C Antibody (C-term) (Cat.#P30217) in K562 cell line lysates (35ug/lane). MYO1C (arrow) was detected using the purified Pab.
	Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with MYO1C antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.