Rabbit Polyclonal Antibody to Myosin Phosphatase

包装: 1G|100G|500G|1KG|100KG

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别名:PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit
应用:WB,IHC
反应种属:Human,Mouse,Rat,Monkey
规格：50μl/100μl

Description
Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN-dependent suppression of HIF1A activity.

Specification
Aliases	PPP1R12A; MBS; MYPT1; Protein phosphatase 1 regulatory subunit 12A; Myosin phosphatase-targeting subunit 1; Myosin phosphatase target subunit 1; Protein phosphatase myosin-binding subunit
Entrez GeneID	4659
Swissprot	O14974
WB Predicted band size	Calculated MW: 115 kDa; Observed MW: 140 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Monkey
Immunogen	The antiserum was produced against synthesized peptide derived from human MYPT1. AA range:661-710
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000
IHC	1/50-1/100
ELISA	1/10000

	Western blot analysis of Myosin Phosphatase in various lysates using Myosin Phosphatase antibody.
	Western blot analysis of Myosin Phosphatase in 293T lysates using MYPT1 antibody.
	Western blot analysis of Myosin Phosphatase in COS7 lysates using Myosin Phosphatase antibody.The lane on the right is blocked with the synthesized peptide.
	Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue using MYPT1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.