中文 
别名:PMYT1; PKMYT1; MYT1 kinase;应用:IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase preferentially phosphorylates and inactivates cell division cycle 2 protein (CDC2), and thus negatively regulates cell cycle G2/M transition. This kinase is associated with the membrane throughout the cell cycle. Its activity is highly regulated during the cell cycle. Protein kinases AKT1/PKB and PLK (Polo-like kinase) have been shown to phosphorylate and regulate the activity of this kinase. Alternatively spliced transcript variants encoding distinct isoforms have been reported.Booher R.N., J. Biol. Chem. 272:22300-22306(1997)Liu F., Mol. Cell. Biol. 17:571-583(1997)Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006) |
| Specification | |
|---|---|
| Aliases | PMYT1; PKMYT1; MYT1 kinase; |
| Entrez GeneID | 9088; |
| Swissprot | Q99640 |
| WB Predicted band size | 54kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Peptide sequence around phosphorylation site of Serine 83(R-V-S(p)-F-R) derived from Human MYT1. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IHC | 1/50-1/100 |
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MYT1 (Phospho-Ser83) antibody P40448 (left)or the same antibody preincubated with blocking peptide (right). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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