Rabbit Polyclonal Antibody to NAT10

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别名:ALP; NET43
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
N-acetyltransferase 10 is an enzyme that in humans is encoded by the NAT10 gene. Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization.

Description

N-acetyltransferase 10 is an enzyme that in humans is encoded by the NAT10 gene. Has protein acetyltransferase activity in vitro. Can acetylate both histones and microtubules. Histone acetylation may regulate transcription and mitotic chromosome de-condensation. Activates telomerase activity by stimulating the transcription of TERT, and may also regulate telomerase function by affecting the balance of telomerase subunit assembly, disassembly, and localization.

Specification
Aliases	ALP; NET43
Swissprot	Q9H0A0
WB Predicted band size	116 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Fusion protein of human NAT10
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1/2000-1/5000

	Gel: 6%SDS-PAGE, Lysate: 50 μg, Lane 1-3: A549 cells, K562 cells, hela cells, Primary antibody: P01572(NAT10 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
	The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P01572(NAT10 Antibody) at dilution 1/40. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P01572(NAT10 Antibody) at dilution 1/40. (Original magnification: ×200)