Rabbit Polyclonal Antibody to NCoR1

包装: 1G|100G|500G|1KG|100KG

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别名:KIAA1047; N-CoR1;
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.Igor Girault, Clin. Cancer Res., Apr 2003; 9: 1259. Xinjian Peng, Carcinogenesis, May 2007; 28: 1000 – 1007. Satoshi Mikawa, Genome Res., May 2007; 17: 586 – 593. Claire M. Banwell, Clin. Cancer Res., Apr 2006; 12: 2004 – 2013.

Description

Mediates transcriptional repression by certain nuclear receptors. Part of a complex which promotes histone deacetylation and the formation of repressive chromatin structures which may impede the access of basal transcription factors. Participates in the transcriptional repressor activity produced by BCL6.Igor Girault, Clin. Cancer Res., Apr 2003; 9: 1259. Xinjian Peng, Carcinogenesis, May 2007; 28: 1000 – 1007. Satoshi Mikawa, Genome Res., May 2007; 17: 586 – 593. Claire M. Banwell, Clin. Cancer Res., Apr 2006; 12: 2004 – 2013.

Specification
Aliases	KIAA1047; N-CoR1;
Entrez GeneID	9611;
Swissprot	O75376
WB Predicted band size	270kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from Internal of human NCoR1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from MDA-MB-435 cells, using NCoR1 antibody P41840.
	Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using NCoR1 antibody P41840.