别名:LY95; CD336; NKP44; NK-p44; dJ149M18.1应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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Natural cytotoxicity triggering receptor 2 is a protein that in humans is encoded by the NCR2 gene. NCR2 has also been designated as CD336(cluster of differentiation?336). NKp44 is a natural cytotoxicity receptor that is is expressed on IL-2-activated human NK cells and may contribute to the increased efficiency of NK cells to mediate tumor cell lysis. NKp44 is composed of one Ig-like extracellular domain, a transmembrane segment, and a cytoplasmic domain. Prolactin up-regulates and cortisol down-regulates the surface expression of NKp44 at the transcriptional level. A cellular ligand for NKp44 (NKp44L) is expressed during HIV-1 infection and is correlated with the progression of CD4+ T cell depletion and an increase of viral load. |
Specification | |
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Aliases | LY95; CD336; NKP44; NK-p44; dJ149M18.1 |
Entrez GeneID | 9436; |
Swissprot | O95944 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide corresponding to a region derived from internal residues of human natural cytotoxicity triggering receptor 2 |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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IHC | 1/50-1/200 |
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42919 at dilution 1/60. |
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Immunohistochemical analysis of paraffin-embedded Human brain tissue using P42919 at dilution 1/60. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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