别名:NFL; NF-L; NF68; CMT1F; CMT2E应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y. |
Specification | |
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Aliases | NFL; NF-L; NF68; CMT1F; CMT2E |
Entrez GeneID | 4747; |
Swissprot | P07196 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein corresponding to a region derived from internal residues of human neurofilament, light polypeptide |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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IHC | 1/25-1/100 |
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Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42745 at dilution 1/20. |
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Immunohistochemical analysis of paraffin-embedded Human esophagus cancer tissue using P42745 at dilution 1/20. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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