Rabbit Polyclonal Antibody to NKX3.1

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:Homeobox protein Nkx-3.1; NKX31; NKX3A;
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
Transcription factor, which binds preferentially the consensus sequence 5′-TAAGT[AG]-3′ and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.Cai Bowen, Cancer Res., Jan 2007; 67: 455 – 464. Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 – 3017. Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 – 1173. Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 – 10690.

Description

Transcription factor, which binds preferentially the consensus sequence 5′-TAAGT[AG]-3′ and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.Cai Bowen, Cancer Res., Jan 2007; 67: 455 – 464. Xiang Li, Mol. Cell. Biol., Apr 2006; 26: 3008 – 3017. Ekatherine Asatiani, Cancer Res., Feb 2005; 65: 1164 – 1173. Carlise R. Bethel, Cancer Res., Nov 2006; 66: 10683 – 10690.

Specification
Aliases	Homeobox protein Nkx-3.1; NKX31; NKX3A;
Entrez GeneID	4824;
Swissprot	Q99801
WB Predicted band size	38kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from N-terminal of human NKX3.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.