别名:MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA应用:IHC
反应种属:Human
规格:50μl/100μl
Description |
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This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
Specification | |
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Aliases | MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA |
Entrez GeneID | 4914; |
Swissprot | P04629 |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide corresponding to residues near the C terminal of human neurotrophic tyrosine kinase, receptor, type 1 |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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IHC | 1/100-1/300 |
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Immunohistochemical analysis of paraffin-embedded Human colon cancer tissue using P42878 at dilution 1/90. |
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Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using P42878 at dilution 1/90. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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