别名:Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen;应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions.Yang C.H., J. Cell Biol. 116:1303-1317(1992).Compton D.A., J. Cell Biol. 116:1395-1408(1992).Maekawa T., J. Cell Sci. 105:589-600(1993). |
Specification | |
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Aliases | Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen; |
Entrez GeneID | 4926; |
Swissprot | Q14980 |
WB Predicted band size | 240kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthesized peptide derived from internal of human NUMA1. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/3000 |
IHC | 1/50-1/100 |
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Western blot analysis of extracts from A549 cells, using NUMA1 antibody P42504. |
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Immunohistochemistry analysis of paraffin-embedded human testis tissue using NUMA1 antibody P42504. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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