Rabbit Polyclonal Antibody to OAT

包装: 1G|100G|500G|1KG|100KG

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别名:DKFZp781A11155; GACR; gyrate atrophy; HOGA; OAT
应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.ana G., Proc. Natl. Acad. Sci. U.S.A. 83:1203-1207(1986).Ramesh V., DNA 5:493-501(1986).

Description

This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome.ana G., Proc. Natl. Acad. Sci. U.S.A. 83:1203-1207(1986).Ramesh V., DNA 5:493-501(1986).

Specification
Aliases	DKFZp781A11155; GACR; gyrate atrophy; HOGA; OAT
Entrez GeneID	4942;
Swissprot	P04181
WB Predicted band size	49kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from Internal of human OAT.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.