Rabbit Polyclonal Antibody to OSR1 (Phospho-Thr185)

包装: 1G|100G|500G|1KG|100KG

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别名:OXSR1; kinase OSR1; Oxidative-stress responsive 1;
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Oxidative-stress responsive 1 gene is located in the vicinity of three others genes – GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stressTamari M., J. Hum. Genet. 44:116-120(1999)Kikuno R., DNA Res. 6-197-205(1999)The MGC Project Team; Genome Res. 14:2121-2127(2004).

Description

Oxidative-stress responsive 1 gene is located in the vicinity of three others genes – GOLGA4, ITGA9 and HYA22 on chromosome 3. These four genes are considered to be candidate tumor suppressors. Oxidative-stress responsive 1 protein has similarity to human Ste20/oxidant stress response kinase-1 and is thought to be involved in the response to oxidative stressTamari M., J. Hum. Genet. 44:116-120(1999)Kikuno R., DNA Res. 6-197-205(1999)The MGC Project Team; Genome Res. 14:2121-2127(2004).

Specification
Aliases	OXSR1; kinase OSR1; Oxidative-stress responsive 1;
Entrez GeneID	9943;
Swissprot	O95747
WB Predicted band size	65kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Peptide sequence around phosphorylation site of threonine185(R-K-T(p)-F-V) derived from Human OSR1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of extracts from HepG2 cells treated with serum using OSR1 (Phospho-Thr185) Antibody P40449.The lane on the right is treated with the antigen-specific peptide.
	Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using OSR1 (Phospho-Thr185) antibody P40449 (left)or the same antibody preincubated with blocking peptide (right).