Rabbit Polyclonal Antibody to PAN3 (C-term)

包装: 1G|100G|500G|1KG|100KG

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别名:PAB-dependent poly(A)-specific ribonuclease subunit PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}, PAB1P-dependent poly(A)-nuclease {ECO:0000255|HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255|HAMAP-Rule:MF_03181}, hPan3, PAN3 {ECO:0000255|HAMAP-Rule:MF_03181}
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
PAN3 is functions in cytoplasmic mRNA decay. It is as part of the Pan nuclease complex, recruits polyadenylate-binding protein which in turn stimulates PAN2 nuclease activity.

Specification
Aliases	PAB-dependent poly(A)-specific ribonuclease subunit PAN3 {ECO:0000255\|HAMAP-Rule:MF_03181}, PAB1P-dependent poly(A)-nuclease {ECO:0000255\|HAMAP-Rule:MF_03181}, PAN deadenylation complex subunit 3 {ECO:0000255\|HAMAP-Rule:MF_03181}, hPan3, PAN3 {ECO:0000255\|HAMAP-Rule:MF_03181}
Entrez GeneID	255967
Swissprot	Q58A45
WB Predicted band size	95.6kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This PAN3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 771-799 amino acids from the C-terminal region of human PAN3.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	Western blot analysis of PAN3 Antibody (C-term) (Cat. #P30612) in Jurkat cell line lysates (35ug/lane). PAN3 (arrow) was detected using the purified Pab.
	PAN3 Antibody (C-term) (Cat. #P30612) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	PAN3 Antibody (C-term) (Cat. #P30612) IHC analysis in formalin fixed and paraffin embedded human cervix carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PAN3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.